New research provides key insight about mitochondrial replacement therapy

OHSU-led study in Nature suggests mitochondrial donors should be carefully selected to avoid transmission of harmful mutations

By Erik Robinson November 30, 2016 Portland, Ore.

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Shoukhrat Mitalipov, Ph.D.

Shoukhrat Mitalipov, Ph.D., director of the OHSU Center for Embryonic Cell and Gene Therapy. (OHSU/Jeffrey Ball)

Mitochondrial replacement therapy

A pipette pulls out the nuclear genetic material from an unfertilized egg –a key step in mitochondrial replacement therapy. The nucleus, or spindle, is visible in the pipette. (OHSU)

ST in human oocytes

Shoukhrat Mitalipov's spindle-transfer technique. (OHSU)