Study: Dangerous E. coli strain blocks gut’s defense mechanism to spread infection

Research from OHSU sheds light on why some bacteria aren’t easily shed by the body

By Angela Yeager October 22, 2025 Portland, Oregon

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Study: Dangerous E. coli strain blocks gut’s defense mechanism to spread infection

From left: Rachael Peterson, B.S., Isabella Rauch, Ph.D., and Marin Miner, B.S. in the Rauch lab. Isabella Rauch, Ph.D., is the senior author on a new study published in Nature that reveals how a dangerous strain of E. coli blocks the body’s immune defenses to spread infection. (OHSU/Christine Torres Hicks)

Isabella Rauch, Ph.D.

Isabella Rauch, Ph.D., is the senior author on a new study published in Nature that reveals how a dangerous strain of E. coli blocks the body’s immune defenses to spread infection. (OHSU/Christine Torres Hicks)

Isabella Rauch, Ph.D. (OHSU)

Study: Dangerous E. coli strain blocks gut’s defense mechanism to spread infection