OHSU researchers develop functional eggs from human skin cells

Research develops proof of concept for treatment of infertility affecting millions

By Erik Robinson September 30, 2025 Portland, Oregon

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Paula Amato, M.D., and Shoukhrat Mitalipov, Ph.D.

Paula Amato, M.D., professor of obstetrics and gynecology in the OHSU School of Medicine, and Shoukhrat Mitalipov, Ph.D., director of the OHSU Center for Embryonic Cell and Gene Therapy. (OHSU/Christine Torres Hicks)

Shoukhrat Mitalipov, Ph.D. (OHSU)

Paula Amato, M.D. (OHSU)

Nuria Marti-Gutierrez, Ph.D. (OHSU)

Shoukhrat Mitalipov, Ph.D. (2013) (OHSU)

Paula Amato, M.D. (OHSU)

A new technique to treat infertility

Researchers at OHSU have demonstrated a new technique to treat infertility by turning skin cells into oocytes, or eggs. Shown here, an image of an oocyte with a bright image of a skin cell nucleus before fertilization. (Oregon Health & Science University)