Protein associated with many diseases fully visualized for first time

Discovery could lead to development of new drugs to treat inflammation, artery disease, cancer and more

By Franny White October 03, 2019 Portland, Oregon

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VIDEO DOWNLOAD: Cardio P2X7 protein receptor animation

An animation shows how the P2X7 protein receptor opens and closes, allowing charged particles to enter a cell and trigger cellular changes. OHSU resarchers used cryoelectron microscopy to obtain the protein's 3D structure for the first time. P2X7 is associated with many diseases, including inflammation, coronary artery disease, cancer and multiple sclerosis. (OHSU)

Cardio P2X7 protein receptor

An illustration shows how the P2X7 protein receptor opens and closes, allowing charged particles to enter a cell and trigger cellular changes. OHSU resarchers used cryoelectron microscopy to obtain the protein's 3D structure for the first time. P2X7 is associated with many diseases, including inflammation, coronary artery disease, cancer and multiple sclerosis. (OHSU)

Steven Mansoor, M.D., Ph.D.

Steven Mansoor, M.D., Ph.D., and colleagues have identified the inner workings of the P2X7 protein receptor, which is associated with inflammation, coronary artery disease, cancer, multiple sclerosis and more. (OHSU)

Steven Mansoor, M.D., Ph.D.