‘Bone in a dish’ opens new window on cancer initiation, metastasis, bone healing

Like real bone, the material developed at OHSU has a 3D mineral structure populated with living cells, providing a unique model to study bone function, diseases, regeneration

By Joe Rojas-Burke August 06, 2019 Portland, Oregon

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Athirasala and Bertassoni

Avathamsa Athirasala, M.Sc.Eng. (left) and Luiz Bertassoni, D.D.S., Ph.D. (OHSU/Joe Rojas-Burke)

Engineered bone tissue

Luiz Bertassoni, D.D.S., Ph.D., shows an engineered material that replicates human bone tissue. The material is being used to explore disease processes such as the origin of metastatic tumors in bone, and as a treatment for large bone injuries. (OHSU/Joe Rojas-Burke)

Engineered bone tissue

Researchers at CEDAR, the Cancer Early Detection Advanced Research Center in the OHSU Knight Cancer Institute, have engineered material that replicates human bone tissue. The material is being used to explore disease processes such as the origin of metastatic tumors in bone, and as a treatment for large bone injuries. (OHSU/Joe Rojas-Burke)

Engineered bone tissue

Avathamsa Athirasala, M.Sc.Eng.

Avathamsa Athirasala, M.Sc.Eng. (OHSU/Joe Rojas-Burke)

Luiz Bertassoni, D.D.S., Ph.D.

Luiz Bertassoni, D.D.S., Ph.D. (OHSU/Kristyna Wentz-Graff)