Research team discovers drug compound that stops cancer cells from spreading

Via a mouse model, OHSU physician-scientists lead effort to hone a drug that inhibits cancer cells from spreading to other areas in the body

By Amanda Gibbs June 22, 2018 Portland, Oregon

Downloads

UW research team

(Left to right) University of Washington researchers: Kevin Felt, Sung-gun Park, Juan Chavez, Jim Bruce, Jared Mohr, Xuefei Zhong, Martin Mathay, Andrew Keller. (Courtesy of the University of Washington)

Cancer motility

Raymond Bergan, M.D., (left) talks with Ryan Gordon, Ph.D., in the OHSU Bergan Basic Research Laboratory, May 23, 2018. A multidisciplinary team has discovered a drug compound that stops cancer cells from spreading throughout the body. (OHSU/Kristyna Wentz-Graff)

Cancer motility

(Left to right) Ryan Gordon, Ph.D., Raymond Bergan, M.D., Zhenzhen Zhang, Ph.D., M.P.H., Limin Zhang, Ph.D., Graham Fowler and Abhi Pattanayak in the OHSU Bergan Basic Research Laboratory, May 23, 2018. A multidisciplinary team has discovered a drug compound that stops cancer cells from spreading throughout the body. (OHSU/Kristyna Wentz-Graff)

Ray Bergan, M.D.

Head, Division of Hematology and Medical Oncology, OHSU School of Medicine; Associate Director, Medical Oncology, OHSU Knight Cancer Institute. (OHSU)

Karl Scheidt, Ph.D.

Karl Scheidt, Ph.D., professor of chemistry and professor of pharmacology; director of the Center for Molecular Innovation and Drug Discovery; and executive director of the NewCures accelerator at Northwestern University. (Lemieux-Jordan/Northwestern University)

Ryan Gordon, Ph.D.

Ryan Gordon, Ph.D., research assistant professor in the OHSU School of Medicine and co-director of the Bergan lab. (OHSU/Kristyna Wentz-Graff)

Li Xu

Dr. Li Xu, Northwestern University in Chicago. (Courtesy of Li Xu)